Doç. Dr. HAKAN ALICI

HAKAN ALICI

Doç. Dr.

ATOM VE MOLEKÜL FİZİĞİ

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Department

FEN FAKÜLTESİ > FİZİK BÖLÜMÜ > ATOM VE MOLEKÜL FİZİĞİ

Temel Alanı

Fen Bilimleri ve Matematik Temel Alanı

Bilim Alanı

Fizik

Akademik Anahtar Kelime

Atom, Molekül ve Lazer Fiziği
Biyofizik

Metrics

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Academic Activity

Education Details

2004 - 2008

GAZİ ÜNİVERSİTESİ

Lisans-Anadal

KASTAMONU FEN-EDEBİYAT FAKÜLTESİ | FİZİK

2010 - 2012

BÜLENT ECEVİT ÜNİVERSİTESİ

Yüksek Lisans-Tezli

FEN BİLİMLERİ ENSTİTÜSÜ | FİZİK

2012 - 2018

BÜLENT ECEVİT ÜNİVERSİTESİ

Doktora

FEN BİLİMLERİ ENSTİTÜSÜ | FİZİK

Articles

WOS.SCI

Novel 1,2,4-triazole-derived Schiff base derivatives: Design, synthesis, and multi-enzyme targeting potential for therapeutic applications

Ozcan, I ,

Alici, H ,

Taslimi, P ,

Tahtaci, H

BIOORGANIC CHEMISTRY Volume 157 | 2025

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis and Characterization of Schiff Bases and Their Ag(I) Complexes Containing 2,5,6-Trisubstituted Imidazothiadiazole Derivatives: Molecular Docking and In Vitro Cytotoxic Effects Against Nonsmall Lung Cancer Cell Line

Mirghani, AH ,

Pehlivanoglu, S ,

Alici, H ,

Tahtaci, H ,

Uysal, S

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Volume 39 | 2025

BM Sürdürebilirlik Etiketleri

WOS.SCI

Effects of the Amyotrophic Lateral Sclerosis-related Q108P Mutation on the Structural Ensemble Characteristics of CHCHD10

Alici, H ,

Uversky, VN ,

Kang, DE ,

Woo, JA ,

Coskuner Weber, Orkid ,

Coskuner-Weber, O

CURRENT PROTEIN & PEPTIDE SCIENCE Volume 26 pages: 201 - 212 | 2025

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, molecular docking, dynamics study and preliminary cytotoxicity study of some coumarin linked imidazothiadiazoles

Kumar, S ,

Sravani, P ,

Gokulakrishnan, S ,

Khushwah, S ,

Metikurki, B ,

Schols, D ,

Alici, H ,

Tahtaci, H ,

Kotha, S ,

Swapna, B ,

Alegaon, SG ,

Karki, SS

JOURNAL OF MOLECULAR STRUCTURE Volume 1321 | 2025

BM Sürdürebilirlik Etiketleri

WOS.SCI

The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10

Alici, H ,

Uversky, VN ,

Kang, DE ,

Woo, JA ,

Coskuner-Weber, O

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS Volume 42 pages: 5607 - 5616 | 2024

BM Sürdürebilirlik Etiketleri

WOS.SCI

Frontotemporal Dementia-Related V57E Mutation Impairs Mitochondrial Function and Alters the Structural Properties of CHCHD10

Alici, H ,

Uversky, VN ,

Liu, T ,

Kang, DE ,

Woo, JA ,

Coskuner-Weber, O

ACS CHEMICAL NEUROSCIENCE Volume 14 pages: 2134 - 2145 | 2023

BM Sürdürebilirlik Etiketleri

WOS.SCI

Effects of the Jokela type of spinal muscular atrophy-related G66V mutation on the structural ensemble characteristics of CHCHD10

Alici, H ,

Uversky, VN ,

Kang, DE ,

Woo, JA ,

Coskuner-Weber, O

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS Volume 91 pages: 739 - 749 | 2023

BM Sürdürebilirlik Etiketleri

WOS.SCI

Novel Thioether-Bridged 2,6-Disubstituted and 2,5,6-Trisubstituted Imidazothiadiazole Analogues: Synthesis, Antiproliferative Activity, ADME, and Molecular Docking Studies

Ozcan, I ,

Akkoç, S ,

Alici, H ,

Çapanlar, S ,

Sahin, O ,

Tahtaci, H

CHEMISTRY & BIODIVERSITY Volume 20 | 2023

BM Sürdürebilirlik Etiketleri

WOS.SCI

Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H-1,2,4-Triazole Ring

Yilmaz, O ,

Çapanlar, S ,

Akkoç, S ,

Alici, H ,

Ozcan, I ,

Tahtaci, H

CHEMISTRYSELECT Volume 7 | 2022

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, Characterization, Theoretical Analyses, and Investigation of Their Biological Activities of Acetovanillone-Derived Novel Benzyl Ethers

Calkilic, NM ,

Alici, H ,

Direkel, S ,

Tahtaci, H

POLYCYCLIC AROMATIC COMPOUNDS Volume 42 pages: 5671 - 5695 | 2022

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, Characterization, Antimicrobial Activity and in Silico Studies of Some Phenyl, Furyl and 1H-1,2,4-Triazole Substituted Benzyl and Alkyl Ethers

Güven, OO ,

Tahtaci, H ,

Altanlar, N ,

Alici, H

CHEMISTRYSELECT Volume 7 | 2022

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives

Das, A ,

Greco, G ,

Kumar, S ,

Catanzaro, E ,

Morigi, R ,

Locatelli, A ,

Schols, D ,

Alici, H ,

Tahtaci, H ,

Ravindran, F ,

Fimognari, C ,

Karki, SS

COMPUTATIONAL BIOLOGY AND CHEMISTRY Volume 97 | 2022

BM Sürdürebilirlik Etiketleri

WOS.SCI

Design and various in silico studies of the novel curcumin derivatives as potential candidates against COVID-19-associated main enzymes

Alici, H ,

Tahtaci, H ,

Demir, K

COMPUTATIONAL BIOLOGY AND CHEMISTRY Volume 98 | 2022

BM Sürdürebilirlik Etiketleri

WOS.SCI

Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia

Alici, H ,

Uversky, VN ,

Kang, DE ,

Woo, JA ,

Coskuner-Weber, O

ACS CHEMICAL NEUROSCIENCE Volume 13 pages: 1273 - 1280 | 2022

BM Sürdürebilirlik Etiketleri

TR DİZİN

Parkinson Hastalığı ile İlişkilendirilen PreNAC Fibril Kesiti ve Onun A53C, A53E, A53G, A53T, A53V Mutasyonlarının Yapısal Kararlılığın Araştırılması

ALICI HAKAN ,
DEMİR KADİR

Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi Volume 16 issue 1 pages: 66 - 76 | 2021

BM Sürdürebilirlik Etiketleri

WOS.SCI

Investigation of Inhibition Effect of Nicotine and Dopamine on Alpha-synuclein

Alici, H

JOURNAL OF COMPUTATIONAL BIOPHYSICS AND CHEMISTRY Volume 20 pages: 477 - 494 | 2021

BM Sürdürebilirlik Etiketleri

WOS.SCI,WOS.IC

Synthesis, structural characterization, biological activity, and theoretical studies of some novel thioether-bridged 2,6-disubstituted imidazothiadiazole analogues

Tunel, H ,

Er, M ,

Alici, H ,

Onaran, A ,

Karakurt, T ,

Tahtaci, H

JOURNAL OF HETEROCYCLIC CHEMISTRY Volume 58 pages: 1321 - 1343 | 2021

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles

Das, A ,

Kumar, S ,

Persoons, L ,

Daelemans, D ,

Schols, D ,

Alici, H ,

Tahtaci, H ,

Karki, SS

HELIYON Volume 7 | 2021

BM Sürdürebilirlik Etiketleri

WOS.SCI

Investigation of the stability and the helix-tail interaction of sCT and its various charged mutants based on comparative molecular dynamics simulations

Alici, H ,

Demir, K

CHEMICAL PHYSICS Volume 542 | 2021

BM Sürdürebilirlik Etiketleri

WOS.ESCI

A Conformational Evaluation for PreNAC(46-56) Fibril Segment of Alpha-synuclein using Molecular Dynamic Simulation Method

Alici, H

KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE Volume 24 pages: 11 - 21 | 2021

BM Sürdürebilirlik Etiketleri

TR DİZİN

HnRNPA2 in LC(286-291) Domain Fibrili ve Onun D290V Mutasyonu Hakkında Teorik Bir Çalışma

ALICI HAKAN

Journal of the Institute of Science and Technology Volume 11 issue 2 pages: 1080 - 1089 | 2021

BM Sürdürebilirlik Etiketleri

WOS.SCI

Synthesis, Characterization, Antimicrobial Evaluation, and Computational Investigation of Substituted Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives

Dagli, M ,

Er, M ,

Karakurt, T ,

Onaran, A ,

Alici, H ,

Tahtaci, H

CHEMISTRYSELECT Volume 5 pages: 11753 - 11763 | 2020

BM Sürdürebilirlik Etiketleri

WOS.SCI

In silico analysis: structural insights about inter-protofilaments interactions for α-synuclein (50-57) fibrils and its familial mutation

Alici, H

MOLECULAR SIMULATION Volume 46 pages: 867 - 878 | 2020

BM Sürdürebilirlik Etiketleri

WOS.SCI

Structural analyses and force fields comparison for NACore (68-78) and SubNACore (69-77) fibril segments of Parkinson's disease

Alici, H

JOURNAL OF MOLECULAR MODELING Volume 26 | 2020

BM Sürdürebilirlik Etiketleri

WOS.SCI

Experimental and theoretical studies of electrochemical oxidation of nicotinamide adenine dinucleotide at the modified SWCNT and graphene oxide

Koçak, I ,

Alici, H

JOURNAL OF MOLECULAR MODELING Volume 26 | 2020

BM Sürdürebilirlik Etiketleri

TR DİZİN

İnsan Kemokin Reseptörü CXCR3'ün N-Terminal Bölgesinin (1-53) Moleküler Dinamik Simülasyon Yöntemi İle Modellenmesi ve Yapısal Analizi

ALICI HAKAN ,
KARACAOĞLAN VOLKAN ,
DEMİR KADİR

Karaelmas Science and Engineering Journal Volume 8 issue 2 pages: 606 - 614 | 2018

BM Sürdürebilirlik Etiketleri

WOS.SCI

Conformational stability of the tetrameric de novo designed hexcoil-Ala helical bundle

Demir, K ,

Alici, H ,

Yasar, F

CHINESE JOURNAL OF PHYSICS Volume 56 pages: 46 - 57 | 2018

BM Sürdürebilirlik Etiketleri

WOS.SCI

On the nuclear properties of ³²S, ⁶⁴Zn, ⁶⁷Zn, ⁸⁹Y, ⁹⁰Zr and ¹⁵³Eu targets used for production of ³²P, ⁶⁴Cu, ⁶⁷Cu, ⁸⁹Sr, ⁹⁰Y and ¹⁵³Sm therapeutic radionuclides

Aytekin, H ,

Baldik, R ,

Alici, H

ANNALS OF NUCLEAR ENERGY Volume 46 pages: 128 - 133 | 2012

BM Sürdürebilirlik Etiketleri

Proceedings

Özet bildiri

INVESTIGATION OF CONFORMATIONAL TRANSITION PROPERTIES OF THE AMYLOID BETA AT NEUTRAL PH AND LOWER PH BY USING MOLECULAR DYNAMIC SIMULATION METHOD

ALICI HAKAN

EURO ASIA 9th. INTERNATIONAL CONGRESS ON APPLIED SCIENCES | 11.8.2021 - 12.8.2021

Özet bildiri

COMPUTATIONAL STUDIES SUGGEST VARIOUS INHIBITORS OF PAPAIN- LIKE PROTEASE OF MERS-COV FROM CURCUMA LONGA

ALICI HAKAN

EUROASIA Congress on Scientific Researches and Recent Trends-VIII | 2.8.2021 - 4.8.2021

Özet bildiri

Theoretical Elucidations about Aggregation Properties of Aβ40 and Aβ42

ALICI HAKAN

USBIK 2021 INTERNATIONAL CONGRESS ON NATURAL SCINENCESS | 26.2.2021 - 28.2.2021

Özet bildiri

The Functionalization of SWCNT andGraphene Oxide for NADH Oxidation: an Experimental and Theoretical Approach

KOÇAK İZZET ,
ALICI HAKAN

3RD INTERNATIONAL EURASIAN CONFERENCE ONBIOLOGICAL AND CHEMICAL SCIENCES | 19.3.2020 - 20.3.2020

Özet bildiri

Molecular insights about α-synuclein (50-57) fibril and its familial mutations

ALICI HAKAN

Turkish Physical Society 35th International Physics Congress (TPS-35) | 4.9.2019 - 8.9.2019

Özet bildiri

A MD study regarding conformational properties and structure-activity relationship of sCT and its variouscharged mutants

ALICI HAKAN ,
DEMİR KADİR

2nd International Eurasian Conference onBiological and Chemical Sciences (EurasianBioChem 2019) | 28.6.2019 - 29.6.2019

Özet bildiri

Comparison of atomistic molecular mechanics force fields for NACore and SubNACore fibrils of Parkinson’sdisease.

ALICI HAKAN

2nd International Eurasian Conference onBiological and Chemical Sciences(EurasianBioChem 2019) | 28.6.2019 - 29.6.2019

Özet bildiri

Computer Aided Prediction of Cxcr3 Binding Site

KARACAOĞLAN VOLKAN ,
ALICI HAKAN ,
CEYHAN DENİZ ,
DEMİR KADİR

2nd International Congress on Advances in Bioscience and Biotechnology (ICABB 2018) | 26.6.2018 - 30.6.2018

Özet bildiri

Structural Analysis of N-Terminal Region (1-53) Of Human Chemokine Receptor CXCR3 By Computational Studies

ALICI HAKAN ,
KARACAOĞLAN VOLKAN ,
DEMİR KADİR

SECOND MEDITERRANEAN NATURAL SCIENCES AND ENGINEERING CONGRESS (MENSEC 2018) | 26.6.2018 - 29.6.2019

Özet bildiri

Investigation Of The Conformational Stability Of Designed Homo Tetrameric Structure

ALICI HAKAN ,
DEMİR KADİR ,
YAŞAR FATİH

From Computational Biophysics To System Biology (CBSB2016) , Ankara/TURKEY | 23.5.2016 - 25.5.2016

Poster

Nuclear Data Evaluation For Production of 32P 64Cu And 90 Y Therapeutic Radionuclides

hüseyin aytekin ,
rıdvan baldık ,
hakan alıcı

Turkish Physics Socieity 28th İnternational Congress | 6.9.2011 - 9.9.2011

Özet bildiri

Nadir Toprak Elementleri Bölgesinde Bulunan Ce Nd Sm Eu Çekirdeklerinin Bazı Taban Durum Özelliklerinin İncelenmesi

hakan alıcı ,
rıdvan baldık

GEFİK 2012 | 13.6.2012 - 15.6.2012

Projects

Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi | Nationally Supported

BEÜ Bilimsel Araştırma Projesi 2015-22794455-03

Tamamlandı

Start 2015 - Finish 2017

Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi | Nationally Supported

1,2,4-Triazol Halkası İçeren Bazı Schıff Bazlarının Sentezi, Karakterizasyonu, in Vitro Asetilkolinesteraz ve Butirilkolinesteraz Enzim İnhibisyonları ve in Silico Moleküler Docking ve ADME Çalışmaları

Devam Ediyor

Start 2024

Books

Bilimsel Kitap

Bölüm : Chapter 33 - Methods to study the effect of solution variables on the conformational dynamics of intrinsically disordered proteins

Advances in Protein Molecular and Structural Biology Methods

ALICI HAKAN ,
HASEKİOĞLU ORKUN ,
N. Uversky Vladimir ,
COŞKUNER WEBER ORKİDE

2022, Elsevier ( Elsevier Academic Press ), None

Administrative Duties

Contact information

Telephone . . . . . 3722911382
E-mail . . . . . hakanalici