HAKAN ALICI

Doç. Dr.

HAKAN ALICI

Doç. Dr.

ATOM VE MOLEKÜL FİZİĞİ

About

Department
FEN FAKÜLTESİ > FİZİK BÖLÜMÜ > ATOM VE MOLEKÜL FİZİĞİ

Temel Alanı
  • Fen Bilimleri ve Matematik Temel Alanı
Bilim Alanı
  • Fizik
Akademik Anahtar Kelime
  • Atom, Molekül ve Lazer Fiziği
  • Biyofizik
Metrics
0 h-index (WOS)
0 Total Cited (WOS)
Academic Activity
Education Details
2004 - 2008
GAZİ ÜNİVERSİTESİ
Lisans-Anadal

KASTAMONU FEN-EDEBİYAT FAKÜLTESİ | FİZİK

2010 - 2012
BÜLENT ECEVİT ÜNİVERSİTESİ
Yüksek Lisans-Tezli

FEN BİLİMLERİ ENSTİTÜSÜ | FİZİK

2012 - 2018
BÜLENT ECEVİT ÜNİVERSİTESİ
Doktora

FEN BİLİMLERİ ENSTİTÜSÜ | FİZİK

Articles
WOS.SCI
Novel 1,2,4-triazole-derived Schiff base derivatives: Design, synthesis, and multi-enzyme targeting potential for therapeutic applications
  • Ozcan, I ,
  • Alici, H ,
  • Taslimi, P ,
  • Tahtaci, H
  • BIOORGANIC CHEMISTRY Volume 157 | 2025

    BM Sürdürebilirlik Etiketleri

    WOS.SCI
    Synthesis and Characterization of Schiff Bases and Their Ag(I) Complexes Containing 2,5,6-Trisubstituted Imidazothiadiazole Derivatives: Molecular Docking and In Vitro Cytotoxic Effects Against Nonsmall Lung Cancer Cell Line
    • Mirghani, AH ,
    • Pehlivanoglu, S ,
    • Alici, H ,
    • Tahtaci, H ,
    • Uysal, S
    • JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Volume 39 | 2025

      BM Sürdürebilirlik Etiketleri

      WOS.SCI
      Effects of the Amyotrophic Lateral Sclerosis-related Q108P Mutation on the Structural Ensemble Characteristics of CHCHD10
      • Alici, H ,
      • Uversky, VN ,
      • Kang, DE ,
      • Woo, JA ,
      • None ,
      • Coskuner-Weber, O
      • CURRENT PROTEIN & PEPTIDE SCIENCE Volume 26 pages: 201 - 212 | 2025

        BM Sürdürebilirlik Etiketleri

        WOS.SCI
        Synthesis, molecular docking, dynamics study and preliminary cytotoxicity study of some coumarin linked imidazothiadiazoles
        • Kumar, S ,
        • Sravani, P ,
        • Gokulakrishnan, S ,
        • Khushwah, S ,
        • Metikurki, B ,
        • Schols, D ,
        • Alici, H ,
        • Tahtaci, H ,
        • Kotha, S ,
        • Swapna, B ,
        • Alegaon, SG ,
        • Karki, SS
        • JOURNAL OF MOLECULAR STRUCTURE Volume 1321 | 2025

          BM Sürdürebilirlik Etiketleri

          WOS.SCI
          The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10
          • Alici, H ,
          • Uversky, VN ,
          • Kang, DE ,
          • Woo, JA ,
          • Coskuner-Weber, O
          • JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS Volume 42 pages: 5607 - 5616 | 2024

            BM Sürdürebilirlik Etiketleri

            WOS.SCI
            Frontotemporal Dementia-Related V57E Mutation Impairs Mitochondrial Function and Alters the Structural Properties of CHCHD10
            • Alici, H ,
            • Uversky, VN ,
            • Liu, T ,
            • Kang, DE ,
            • Woo, JA ,
            • Coskuner-Weber, O
            • ACS CHEMICAL NEUROSCIENCE Volume 14 pages: 2134 - 2145 | 2023

              BM Sürdürebilirlik Etiketleri

              WOS.SCI
              Effects of the Jokela type of spinal muscular atrophy-related G66V mutation on the structural ensemble characteristics of CHCHD10
              • Alici, H ,
              • Uversky, VN ,
              • Kang, DE ,
              • Woo, JA ,
              • Coskuner-Weber, O
              • PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS Volume 91 pages: 739 - 749 | 2023

                BM Sürdürebilirlik Etiketleri

                WOS.SCI
                Novel Thioether-Bridged 2,6-Disubstituted and 2,5,6-Trisubstituted Imidazothiadiazole Analogues: Synthesis, Antiproliferative Activity, ADME, and Molecular Docking Studies
                • Ozcan, I ,
                • Akkoç, S ,
                • Alici, H ,
                • Çapanlar, S ,
                • Sahin, O ,
                • Tahtaci, H
                • CHEMISTRY & BIODIVERSITY Volume 20 | 2023

                  BM Sürdürebilirlik Etiketleri

                  WOS.SCI
                  Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H-1,2,4-Triazole Ring
                  • Yilmaz, O ,
                  • Çapanlar, S ,
                  • Akkoç, S ,
                  • Alici, H ,
                  • Ozcan, I ,
                  • Tahtaci, H
                  • CHEMISTRYSELECT Volume 7 | 2022

                    BM Sürdürebilirlik Etiketleri

                    WOS.SCI
                    Synthesis, Characterization, Theoretical Analyses, and Investigation of Their Biological Activities of Acetovanillone-Derived Novel Benzyl Ethers
                    • Calkilic, NM ,
                    • Alici, H ,
                    • Direkel, S ,
                    • Tahtaci, H
                    • POLYCYCLIC AROMATIC COMPOUNDS Volume 42 pages: 5671 - 5695 | 2022

                      BM Sürdürebilirlik Etiketleri

                      WOS.SCI
                      Synthesis, Characterization, Antimicrobial Activity and in Silico Studies of Some Phenyl, Furyl and 1H-1,2,4-Triazole Substituted Benzyl and Alkyl Ethers
                      • Güven, OO ,
                      • Tahtaci, H ,
                      • Altanlar, N ,
                      • Alici, H
                      • CHEMISTRYSELECT Volume 7 | 2022

                        BM Sürdürebilirlik Etiketleri

                        WOS.SCI
                        Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives
                        • Das, A ,
                        • Greco, G ,
                        • Kumar, S ,
                        • Catanzaro, E ,
                        • Morigi, R ,
                        • Locatelli, A ,
                        • Schols, D ,
                        • Alici, H ,
                        • Tahtaci, H ,
                        • Ravindran, F ,
                        • Fimognari, C ,
                        • Karki, SS
                        • COMPUTATIONAL BIOLOGY AND CHEMISTRY Volume 97 | 2022

                          BM Sürdürebilirlik Etiketleri

                          WOS.SCI
                          Design and various in silico studies of the novel curcumin derivatives as potential candidates against COVID-19-associated main enzymes
                          • Alici, H ,
                          • Tahtaci, H ,
                          • Demir, K
                          • COMPUTATIONAL BIOLOGY AND CHEMISTRY Volume 98 | 2022

                            BM Sürdürebilirlik Etiketleri

                            WOS.SCI
                            Structures of the Wild-Type and S59L Mutant CHCHD10 ProteinsImportant in Amyotrophic Lateral Sclerosis-FrontotemporalDementia
                            • Alici, H ,
                            • Uversky, VN ,
                            • Kang, DE ,
                            • Woo, JA ,
                            • Coskuner-Weber, O
                            • ACS CHEMICAL NEUROSCIENCE Volume 13 pages: 1273 - 1280 | 2022

                              BM Sürdürebilirlik Etiketleri

                              TR DİZİN
                              Parkinson Hastalığı ile İlişkilendirilen PreNAC Fibril Kesiti ve Onun A53C, A53E, A53G, A53T, A53V Mutasyonlarının Yapısal Kararlılığın Araştırılması
                              • ALICI HAKAN ,
                              • DEMİR KADİR

                              Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi Volume 16 issue 1 pages: 66 - 76 | 2021

                              BM Sürdürebilirlik Etiketleri

                              WOS.SCI
                              Investigation of Inhibition Effect of Nicotine and Dopamine on Alpha-synuclein
                              • Alici, H
                              • JOURNAL OF COMPUTATIONAL BIOPHYSICS AND CHEMISTRY Volume 20 pages: 477 - 494 | 2021

                                BM Sürdürebilirlik Etiketleri

                                WOS.SCI,WOS.IC
                                Synthesis, structural characterization, biological activity, and theoretical studies of some novel thioether-bridged 2,6-disubstituted imidazothiadiazole analogues
                                • Tunel, H ,
                                • Er, M ,
                                • Alici, H ,
                                • Onaran, A ,
                                • Karakurt, T ,
                                • Tahtaci, H
                                • JOURNAL OF HETEROCYCLIC CHEMISTRY Volume 58 pages: 1321 - 1343 | 2021

                                  BM Sürdürebilirlik Etiketleri

                                  WOS.SCI
                                  Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles
                                  • Das, A ,
                                  • Kumar, S ,
                                  • Persoons, L ,
                                  • Daelemans, D ,
                                  • Schols, D ,
                                  • Alici, H ,
                                  • Tahtaci, H ,
                                  • Karki, SS
                                  • HELIYON Volume 7 | 2021

                                    BM Sürdürebilirlik Etiketleri

                                    WOS.SCI
                                    Investigation of the stability and the helix-tail interaction of sCT and its various charged mutants based on comparative molecular dynamics simulations
                                    • Alici, H ,
                                    • Demir, K
                                    • CHEMICAL PHYSICS Volume 542 | 2021

                                      BM Sürdürebilirlik Etiketleri

                                      WOS.ESCI
                                      A Conformational Evaluation for PreNAC(46-56) Fibril Segment of Alpha-synuclein using Molecular Dynamic Simulation Method
                                      • Alici, H
                                      • KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE Volume 24 pages: 11 - 21 | 2021

                                        BM Sürdürebilirlik Etiketleri

                                        TR DİZİN
                                        HnRNPA2 in LC(286-291) Domain Fibrili ve Onun D290V Mutasyonu Hakkında Teorik Bir Çalışma
                                        • ALICI HAKAN

                                        Journal of the Institute of Science and Technology Volume 11 issue 2 pages: 1080 - 1089 | 2021

                                        BM Sürdürebilirlik Etiketleri

                                        WOS.SCI
                                        Synthesis, Characterization, Antimicrobial Evaluation, and Computational Investigation of Substituted Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives
                                        • Dagli, M ,
                                        • Er, M ,
                                        • Karakurt, T ,
                                        • Onaran, A ,
                                        • Alici, H ,
                                        • Tahtaci, H
                                        • CHEMISTRYSELECT Volume 5 pages: 11753 - 11763 | 2020

                                          BM Sürdürebilirlik Etiketleri

                                          WOS.SCI
                                          In silico analysis: structural insights about inter-protofilaments interactions for α-synuclein (50-57) fibrils and its familial mutation
                                          • Alici, H
                                          • MOLECULAR SIMULATION Volume 46 pages: 867 - 878 | 2020

                                            BM Sürdürebilirlik Etiketleri

                                            WOS.SCI
                                            Structural analyses and force fields comparison for NACore (68-78) and SubNACore (69-77) fibril segments of Parkinson's disease
                                            • Alici, H
                                            • JOURNAL OF MOLECULAR MODELING Volume 26 | 2020

                                              BM Sürdürebilirlik Etiketleri

                                              WOS.SCI
                                              Experimental and theoretical studies of electrochemical oxidation of nicotinamide adenine dinucleotide at the modified SWCNT and graphene oxide
                                              • Koçak, I ,
                                              • Alici, H
                                              • JOURNAL OF MOLECULAR MODELING Volume 26 | 2020

                                                BM Sürdürebilirlik Etiketleri

                                                TR DİZİN
                                                İnsan Kemokin Reseptörü CXCR3'ün N-Terminal Bölgesinin (1-53) Moleküler Dinamik Simülasyon Yöntemi İle Modellenmesi ve Yapısal Analizi
                                                • ALICI HAKAN ,
                                                • KARACAOĞLAN VOLKAN ,
                                                • DEMİR KADİR

                                                Karaelmas Science and Engineering Journal Volume 8 issue 2 pages: 606 - 614 | 2018

                                                BM Sürdürebilirlik Etiketleri

                                                WOS.SCI
                                                Conformational stability of the tetrameric de novo designed hexcoil-Ala helical bundle
                                                • Demir, K ,
                                                • Alici, H ,
                                                • Yasar, F
                                                • CHINESE JOURNAL OF PHYSICS Volume 56 pages: 46 - 57 | 2018

                                                  BM Sürdürebilirlik Etiketleri

                                                  WOS.SCI
                                                  On the nuclear properties of 32S, 64Zn, 67Zn, 89Y, 90Zr and 153Eu targets used for production of 32P, 64Cu, 67Cu, 89Sr, 90Y and 153Sm therapeutic radionuclides
                                                  • Aytekin, H ,
                                                  • Baldik, R ,
                                                  • Alici, H
                                                  • ANNALS OF NUCLEAR ENERGY Volume 46 pages: 128 - 133 | 2012

                                                    BM Sürdürebilirlik Etiketleri

                                                    Proceedings
                                                    Özet bildiri
                                                    INVESTIGATION OF CONFORMATIONAL TRANSITION PROPERTIES OF THE AMYLOID BETA AT NEUTRAL PH AND LOWER PH BY USING MOLECULAR DYNAMIC SIMULATION METHOD
                                                    • ALICI HAKAN

                                                    EURO ASIA 9th. INTERNATIONAL CONGRESS ON APPLIED SCIENCES | 11.8.2021 - 12.8.2021

                                                    Özet bildiri
                                                    COMPUTATIONAL STUDIES SUGGEST VARIOUS INHIBITORS OF PAPAIN- LIKE PROTEASE OF MERS-COV FROM CURCUMA LONGA
                                                    • ALICI HAKAN

                                                    EUROASIA Congress on Scientific Researches and Recent Trends-VIII | 2.8.2021 - 4.8.2021

                                                    Özet bildiri
                                                    Theoretical Elucidations about Aggregation Properties of Aβ40 and Aβ42
                                                    • ALICI HAKAN

                                                    USBIK 2021 INTERNATIONAL CONGRESS ON NATURAL SCINENCESS | 26.2.2021 - 28.2.2021

                                                    Özet bildiri
                                                    The Functionalization of SWCNT andGraphene Oxide for NADH Oxidation: an Experimental and Theoretical Approach
                                                    • KOÇAK İZZET ,
                                                    • ALICI HAKAN

                                                    3RD INTERNATIONAL EURASIAN CONFERENCE ONBIOLOGICAL AND CHEMICAL SCIENCES | 19.3.2020 - 20.3.2020

                                                    Özet bildiri
                                                    Molecular insights about α-synuclein (50-57) fibril and its familial mutations
                                                    • ALICI HAKAN

                                                    Turkish Physical Society 35th International Physics Congress (TPS-35) | 4.9.2019 - 8.9.2019

                                                    Özet bildiri
                                                    A MD study regarding conformational properties and structure-activity relationship of sCT and its variouscharged mutants
                                                    • ALICI HAKAN ,
                                                    • DEMİR KADİR

                                                    2nd International Eurasian Conference onBiological and Chemical Sciences (EurasianBioChem 2019) | 28.6.2019 - 29.6.2019

                                                    Özet bildiri
                                                    Comparison of atomistic molecular mechanics force fields for NACore and SubNACore fibrils of Parkinson’sdisease.
                                                    • ALICI HAKAN

                                                    2nd International Eurasian Conference onBiological and Chemical Sciences(EurasianBioChem 2019) | 28.6.2019 - 29.6.2019

                                                    Özet bildiri
                                                    Computer Aided Prediction of Cxcr3 Binding Site
                                                    • KARACAOĞLAN VOLKAN ,
                                                    • ALICI HAKAN ,
                                                    • CEYHAN DENİZ ,
                                                    • DEMİR KADİR

                                                    2nd International Congress on Advances in Bioscience and Biotechnology (ICABB 2018) | 26.6.2018 - 30.6.2018

                                                    Özet bildiri
                                                    Structural Analysis of N-Terminal Region (1-53) Of Human Chemokine Receptor CXCR3 By Computational Studies
                                                    • ALICI HAKAN ,
                                                    • KARACAOĞLAN VOLKAN ,
                                                    • DEMİR KADİR

                                                    SECOND MEDITERRANEAN NATURAL SCIENCES AND ENGINEERING CONGRESS (MENSEC 2018) | 26.6.2018 - 29.6.2019

                                                    Özet bildiri
                                                    Investigation Of The Conformational Stability Of Designed Homo Tetrameric Structure
                                                    • ALICI HAKAN ,
                                                    • DEMİR KADİR ,
                                                    • YAŞAR FATİH

                                                    From Computational Biophysics To System Biology (CBSB2016) , Ankara/TURKEY | 23.5.2016 - 25.5.2016

                                                    Poster
                                                    Nuclear Data Evaluation For Production of 32P 64Cu And 90 Y Therapeutic Radionuclides
                                                    • hüseyin aytekin ,
                                                    • rıdvan baldık ,
                                                    • hakan alıcı

                                                    Turkish Physics Socieity 28th İnternational Congress | 6.9.2011 - 9.9.2011

                                                    Özet bildiri
                                                    Nadir Toprak Elementleri Bölgesinde Bulunan Ce Nd Sm Eu Çekirdeklerinin Bazı Taban Durum Özelliklerinin İncelenmesi
                                                    • hakan alıcı ,
                                                    • rıdvan baldık

                                                    GEFİK 2012 | 13.6.2012 - 15.6.2012

                                                    Projects
                                                    Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi | Nationally Supported
                                                    BEÜ Bilimsel Araştırma Projesi 2015-22794455-03
                                                    Tamamlandı

                                                    Start 2015 - Finish 2017

                                                    Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi | Nationally Supported
                                                    1,2,4-Triazol Halkası İçeren Bazı Schıff Bazlarının Sentezi, Karakterizasyonu, in Vitro Asetilkolinesteraz ve Butirilkolinesteraz Enzim İnhibisyonları ve in Silico Moleküler Docking ve ADME Çalışmaları
                                                    Devam Ediyor

                                                    Start 2024

                                                    Books
                                                    Bilimsel Kitap

                                                    Bölüm : Chapter 33 - Methods to study the effect of solution variables on the conformational dynamics of intrinsically disordered proteins
                                                    Advances in Protein Molecular and Structural Biology Methods
                                                    • ALICI HAKAN ,
                                                    • HASEKİOĞLU ORKUN ,
                                                    • N. Uversky Vladimir ,
                                                    • COŞKUNER WEBER ORKİDE

                                                    2022, Elsevier ( Elsevier Academic Press ), None

                                                    Administrative Duties
                                                    Contact information
                                                    • Telephone . . . . . 3722911382
                                                    • E-mail . . . . . hakanalici